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D C Mash Selected Research

Ibogaine (Endabuse)

7/2006Nature-inspired indolyl-2-azabicyclo[2.2.2]oct-7-ene derivatives as promising agents for the attenuation of withdrawal symptoms: synthesis of 20-desethyl-20-hydroxymethyl-11-demethoxyibogaine.
5/2001In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats.
9/2000Ibogaine: complex pharmacokinetics, concerns for safety, and preliminary efficacy measures.
9/2000Noribogaine (12-hydroxyibogamine): a biologically active metabolite of the antiaddictive drug ibogaine.

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D C Mash Research Topics

Disease

4Parkinson Disease (Parkinson's Disease)
05/2011 - 09/2000
3Alzheimer Disease (Alzheimer's Disease)
10/2009 - 06/2000
3Substance-Related Disorders (Drug Abuse)
01/2007 - 09/2000
2Cocaine-Related Disorders (Cocaine Addiction)
01/2013 - 01/2007
2Substance Withdrawal Syndrome (Withdrawal Symptoms)
07/2006 - 09/2000
2Memory Disorders (Memory Loss)
06/2001 - 01/2001
1Tauopathies
08/2013
1Paralysis (Palsy)
08/2013
1Lewy Body Disease (Lewy Body Dementia)
08/2013
1Huntington Disease (Huntington's Disease)
10/2009
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
10/2009
1Parkinsonian Disorders (Parkinsonism)
03/2004
1Cognitive Dysfunction
06/2001
1Tremor (Tremors)
05/2001
1Delirium
12/2000
1Basal Ganglia Diseases (Basal Ganglia Disease)
09/2000
1Fatigue
09/2000
1Hypertrophy
06/2000

Drug/Important Bio-Agent (IBA)

4Ibogaine (Endabuse)IBA
07/2006 - 09/2000
2Dopamine (Intropin)FDA LinkGeneric
05/2011 - 03/2001
2Proteins (Proteins, Gene)FDA Link
01/2007 - 03/2004
2Pharmaceutical PreparationsIBA
11/2003 - 09/2000
2Messenger RNA (mRNA)IBA
11/2003 - 09/2000
2Dopamine Agents (Dopaminergic Agents)IBA
03/2001 - 09/2000
2Cholinergic Agents (Cholinergics)IBA
01/2001 - 06/2000
2GalaninIBA
01/2001 - 06/2000
1SynucleinsIBA
08/2013
1Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
01/2013
1CatecholsIBA
05/2011
1Aldehyde DehydrogenaseIBA
05/2011
1CatecholaminesIBA
05/2011
1Norepinephrine (Noradrenaline)FDA LinkGeneric
05/2011
1AcidsIBA
05/2011
1Cyanobacteria ToxinsIBA
10/2009
1Amino AcidsFDA Link
10/2009
1beta-N-methylamino-L-alanine (beta-methylamino-L-alanine)IBA
10/2009
120- desethyl- 20- hydroxymethyl- 11- demethoxyibogaineIBA
07/2006
1CannabinoidsIBA
11/2003
1SarinIBA
06/2001
1noribogaineIBA
05/2001
1Levodopa (L Dopa)FDA LinkGeneric
03/2001
1SCH 23390IBA
03/2001
1Cocaine (Cocaine HCl)IBA
12/2000
12beta- carbomethoxy- 3beta- (4- iodophenyl)tropane (Iometopane)IBA
12/2000
1Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
09/2000
1AlkaloidsIBA
09/2000
1Opiate AlkaloidsIBA
09/2000
1Galanin Receptors (Galanin Receptor)IBA
06/2000
1Acetylcholine (Acetylcholine Chloride)FDA Link
06/2000
1Neurotransmitter Agents (Neurotransmitter)IBA
06/2000